Global Toxicology and Risk Assessment

Genetic Toxicology

Genetic Toxicology is the branch which deals with the study of the damages to the genes by means of chemical or Physical factors. Most of the damages to the genetic materials such as DNA and RNA are mostly repaired, if the process had a faulty mechanism in repairing or the process is not functional timely and correctly, these changes or the damages cause mutations and might tend to alteration or deletion of a particular gene. This Genetic Toxicity is thus defined as the changes or the effects to the genetic material resulting in inheritable or mutational defects. Various changes include breakage of the Chromosomes (clastogenesis), mutagenesis, aneugenesis or recombinations are some of the possible changes that might be alter the Genetic Material.