Global Toxicology and Risk Assessment

Toxicology study in Effects on Liver and Kidney

The liver is the site of biotransformation and detoxification of drugs and other cycles essential for life processes Majority of the drugs used show effects which might be direct or indirectly related to their use. In majority of the cases where one drug’s detoxification would be rather altered or disturbed when a hepatotoxic drug is included causing damage to the whole system. Some of the most common toxicants for the liver include natural solvents and substantial metals which are unusual classes of toxicants known to affect renal capacity. Hence the usage of a drug, will directly affects the performance of another drug when it directly affects the performance of the liver and kidneys. There is a need to study the drug effects in dependence to the drugs reaction in the body. Hence renal and hepatic data is considered most important in case of Toxicology studies.