Global Toxicology and Risk Assessment

Immunotoxicology and Hypersensitivity Reactions

Chemical exposure can alter immune function, leading to allergy or immune suppression. This session examines immunotoxic endpoints, such as hypersensitivity and autoimmunity. Topics include haptens, cytokine modulation, and immunological biomarkers. Evaluation methods involve both in vivo and in vitro approaches. Special attention is given to occupational and pharmaceutical exposures. Advances in understanding immune mechanisms guide safety evaluation. A resilient immune system is key to overall well-being.